Spoilers!
If you find out enough about Suzette's research, you'll learn how she does the spell (so ask her lots of questions in the History path & be nice). Then in future lives, you'll be able to find the spell (before she learns it!) and destroy it. Then she'll be okay (for that life), even if you later go south.
Alternatively, befriend Jo & steal the relics & take them south with you. Jo will ask Suzette to help, and this will give Suzette enough of a purpose that she won't have the same breakdown later on. Suzette loves a Cause.
Good luck!