Hi
I installed the lastest 3.50HF with all lastest framework (Random,Unrestgricted, Poisonous, Scoring, Megapack, All Elusive) and The Brothers as well as Random mission work both fine...Are u sure you correctly installed the last framework (by deleting all chunckXpatch X before) with the correct packagefinition.txt file ?
In case of, try to make a clean with your mods into the Runtime folder, delete all '__pycache__' folders you'll find into the Framework folder and put this packagedefinition.txt (it's the last with a clean installation) :
https://drive.google.com/file/d/12mruMEJdqgO_i1bfIqCiaK91gedDrRP1/view?usp=shari...
Then, try to install Framework again