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Biology class is always available, but the insect attack only happens once before you need to sleep to reset it!

After getting stung, go sleep!

thank you for the help :D
Also, if I skipped Cless's medical class, can we retake it again with sleep reset?

The medical class is one time! It's just to introduce you to him!

oh no.... I pressed new game plus and locked myself from his medical class now... I guess I won't continue this save until next update. Thank you for your hard work, indivi!

You can't lock yourself out! It's more like, doing the medical class is the requirement to meeting Cless. Once you do so, it's served its purpose!