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Fusion 2.5 apps/games usually have this problem. The windows defender pops up and says it could be a threat. Pick the "read more" option or what it's called and "run anyway". if you have another anti-virus software I don't know how to help you sadly.

McAfee allows me to restore the file back to its location, but when i try to run it again, it just puts it back into quarantine

You might have to got into the settings and allow it to run the game, somehow. You might have to Google it :/