I think I'm too late to answer this, but here's the answer:
LIKO-12 has some basic limitations, but those can be bypassed by many ways, for example, you can store additional sprites sheets in the code, with gzip compression.
Never too late for an answer :) I'm just a hobbyist who dabbles in game making, so I don't mind waiting for an answer. Are there code limits? Like how Pico-8 limits the total amount of code. That to me is the big one, since I tend to make games that have lots of text.