Emerald Bracelet is my go to for dealing with curses (along with enough space to place an adjacent 2x2 curse when you get hit with the big one)
Cleansing Potion can clear poison. I usually either burst poison enemies down or counter the poison with regeneration (but this will fail if you have more poison stacked than your max health, so I keep a cleanse or two on had to reset if I get too close)