What a cool take on the theme! I really liked the levels and the level select screen.
My only criticism would be to make the instructions more clear and more easy to follow. Its easy to throw a text of instructions at people, but I think it would have been much better to have the first level be an interactive tutorial. Also the items that could be picked up should have some sort of visual cue, like an outline of some sort. For example, at first, it was really hard to find the fire extinguisher, because it was red, and when the alarm fired off and the level turned red, it was hard to spot it.
Despite that, this game is awesome.