About a month ago I played through a couple saves to day 100 clearing the debt, only did notice board quests (no main quest or story slave quests), default start with both me and starting slave as beastkin cats, (made the second save to see if I could make the debt goal faster) hadn't played any version before that though I did play Strive1 a bunch.
In the first save I didn't get a second slave till day 40 or so, and that was when I cleared my first bandit cave, I managed to clear every debt goal getting my third and fourth slaves around days 70-80, made the 86k for day 100 with about a week to spare.
In the second save I bought additional slaves as I finished making things for them to do and had over 40k by day 50 and well over 100k by day 70, no obedience issues even as I fill my mansion immediately after upgrading capacity once I reached the 100k gold milestone, and I easily spent tens of thousands of gold on random junk and exotic slaves during those first 100 days if not over 100k.
I'm not sure how specific RP styles would change being able to make the debt goals, but for obedience unless you are specifically ignoring classes with social abilities it shouldn't be too difficult to keep a full mansion happy (or at least obedient). Given that neither of my runs were done with a combat focus that might be a point of difficulty, though some people say combat is better money than gathering.
By the way with the crafting things taking less than one 6h turn to complete you can queue multiple crafts and finish two or 3 if them in one turn if you have multiple things you want to make.
I missed playing the hour by hour versions so maybe my perception on the 6h turns being reasonable is skewed from that.