Fantastic visuals. I can't overstate how impressed I was with your sprite art and animation. The cutscenes at the beginning and end were a great touch too.
Main gripe I had with the gameplay was that there are so many enemies constantly spawning that it's really easy to build up a ton of time, somewhat invalidating the game's loop mechanic. I was able to get 4 of the 6 weapons and defeat the boss on the first loop.
A map that revealed itself as you explored would have been nice. For most of my time playing I didn't have a good sense of where I or anything I had already been to was.
The doors to houses didn't look like doors to me at first. It took me a little while to realize what they were. I think they could be bigger and more "door-like".
The frame rate drops when you use the melee weapons was jarring. I'm assuming that was intentional and meant as a hitlag effect, but it's way too drastic.
Minor thing, but I ran into a bug where a sign's text remained on screen after leaving it. I was able to make it go away by approaching the sign again and leaving a second time.
Overall, this was a really impressive jam entry. One of the best I've played from this jam so far!