I don't think this is exactly a solution. Because yes, curses, poison and burn are not a problem when you have a "good build" (op enough to kill enemies in one turn). But that feels a bit wrong, to purely rely on glass cannons only as defences are pointless for certain fights, specially when you continue in endless (I mean it makes sense for endless to eventually trade defences for more damage, but not feeling the need to start without any def right away). So you both got some point, you can play around bad mechanics but also "playing around" as for now is mostly restricted to get as much damage output as possible:)