As there is a bit that you have not explained, there are a few possible problems. A lack of memory or CPU are almost never the cause, though the game can sometimes behave like that. That image provides little relevant information besides that you appear to be using a Windows OS.
The game loads a lot of files at the same time during the first loading screen, which can cause the game to be unresponsive for a few seconds. Clicking on the game window during that period can cause Windows to treat it as a crashed program. If the game is simply slow to load, then it could be a graphics issue between the Godot Engine and your hardware/drivers.
An issue that rarely causes crashing on start is a corrupt settings file. This thread details how to handle it: https://itch.io/t/1821316/load-screen-crash-error. Even if that is not your issue, the Debug mod will provide better feedback from the game.
Not all mods are safe to apply to the current version of the game, some mods can conflict with each other, and incorrect installation mods or altered folder paths can also cause similar issues. As you have not listed the mods, I cannot tell you whether they are related. The Bugfix mod will fix some issues, but can create new conflicts. If mods are a source of problems, then the solution is usually to extract a new Strive program folder.