Plague Inc was definitely the inspiration for making this game. The idea was "Plague Inc in reverse". It was early 2020 and I wanted to build out a simulation to see what would happen if COVID ended up spreading outside of China to the rest of the world, how would containment & mitigation strategies affect disease replication & national economies. As much as possible, I used real epidemiological models & formulas to build the game's "disease engine".
Unexpectedly, the game seems to do a pretty good job predicting what ended up happening--riots and economic turmoil. Although one possibility I did not add to the game was that the vaccine would end up not ending the pandemic--because at that time it was understood that vaccines prevent diseases. Our understanding of what vaccines do now has shifted. Looks like I got that bit wrong.