Phenomenal level of polish and very creative implementation of the theme. Randomization as a mechanic is so easy to be frustrating, but being able to loop through the attacks rapidly - and the fact that they were all both useful and fun (bonus for great sfx for each) makes it very satisfying to see them all in use.
The gameplay loop ramps up nicely towards that "enemy melting" phase that become more and more fun to play, and the way the upgrades work made me want to keep seeing all of the different dice I could get, and also how large the bullets could become. Bonus points also towards making you choose "dice" or "stat" before you can see which dice are available.
As others have pointed out, the one "balance" issue is you quickly realize you can rapidly spam attacks and basically never lose (though I see in one of your comments, you've already addressed a fix for this). But for 48 hours, this is absolutely a solid foundation for a real game worth paying for. If this is not in the top 100 I will be very surprised. Excellent job!