Hello.
Do you have all the necessary files in the folder with the executable?
The folder in which you have the D.R.U.N.K.exe should have the following folders and files:
-D.R.U.N.K_Data
-Mono
-D.R.U.N.K.exe
-UnityCrashHandler64.exe
-UnityPlayer.dll
I downloaded the Christmas edition just now and there doesn't seem to be anything wrong with the game itself.