Nice! collapsing stream and modulation rows definitely makes sense. I also had requests for something like this before so I think this would be a nice addition.
Regarding the macro placement I want to keep these together with the rest of the modulation system (things with similar purpose and interaction) to make the UI easier to understand.
The color editor: I see your point but I prefer to keep things simple. Sure, a decent color scheme is important, maybe even light/dark versions but making this fully customizable is definitely not top priority at the moment
The modulator dots are not a bad idea but probably would not work too well with the modulation polarity buttons and I’m not sure how things would fit if you assign many modulators to one knob.
The +/- buttons and the lines for grouping in/out/adsr knobs are great Thanks for sharing your ideas!