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For more explicit directions, because this is a common problem (rot13) - 

Rnpu cbgvba lbh pensg zbqvsvrf gur jbeyq zrgre - cbfvgvir be artngvir, qrcraqvat ba vs vg'f Yvtug be Qnex nffbpvngrq. Trggvat gur jbeyq zrgre gb gur znkvzhz / zvavzhz (500) va rnpu nern haybpxf gur bgure 2 Fbatf. (Juvyr 500 fbhaqf yvxr n ybg, rnpu znk yriry cbgvba tvirf 25, zhygvcyvrq ol hc gb 10 qrcraqvat ba gur crepragntr erfhygf.)

What does any of this actually mean because I've went through and made plenty of Hades potions in every location and research plenty of times in every location again and I've found nothing

Qvq lbh znxr fher gb frnepu ng gur ybpngvbaf jurer gur qrznaq sbe Yvtug be Qnex vf mreb?

Yup