Could it be any 12 keys we like or does it have to be only those ones?
It can be any 12 keys you'd like. If you want to use classic keyboard controls like arrow keys and WASD I think that's a good choice for convenience because people will be playing on a computer keyboard and not the Nokia's keypad. If you want to go as far as emulating the Nokia's keypad by choosing a block of keys that are close together (ex. 123qweasdzxc) go for it!