No one has asked about this engine yet. I downloaded Intersect to try to confirm compatibility but for some reason I can't get it up and running, so I have to go with educated guesses on this one.
I think it will work, though. Intersect supports 32px tiles, right? And it looks like it doesn't have strict requirements on the size of the images that contain tiles, based on the tilesets included with the engine.
It also looks like it uses the same type of autotiles that RPG Maker uses? That would be great as we have that format already.
If you want to try it out, a refund is always an option if it doesn't work out. :)