If you got to this point, I'm pretty sure you already have guile-3.0-dev (if not, simply install it from apt, the version in debian bullseye ought to work fine), so let's continue from there.
First you need to get Guile-SDL2 0.5.0, run the good ol' configure, make, install. Next, do the same for Tsukundere with any release from the 0.2.x branch (ye old 0.2.3 has gathered some dust, but ought to work). Finally, rerun ./configure and you should find it :)