The persistent save files are located /Library/RenPy/game_directory but it sometimes sees different downloads as different games. If you want to start completely fresh then those are the files you need to delete or overwrite.
I'm not on patreon because patreon does not allow incest content and I refuse to make my games where it needs a patch in order to play them. Also Patreon has gone out of its way to ban people without warning and without stating the reasons why especially when it comes to adult content creators. As such I have no real wish to use them.