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I'm afraid I won't be able to substantially improve the accessibility of the Windows version in the foreseeable future. Does your screen reader do OCR (recognizing text from pictures)? If so, the normal Windows binary may work for you. However, there are two kinds of fonts, the smaller one is for text and it's overlayed on the larger one for the map symbols. If the OCR fails to cope with two kinds of fonts, an option can be toggled to only have the big font for everything.

I do hope the gameplay works. Several people had fun with it. Some finished shorter scenarios, some even won the longest one. However, the map is quite complex, because you have several party members to control. Not at the same time, but a few moves of one character, a few of another, for three or more party members usually. Quite a bit of tactical consideration about which character stands where in relation to the others, map obstacles, enemies. If you'd prefer something simpler, I strongly recommend classical text-based roguelike games, such as Angband, where you only control one character (usually). Many of them should be very accessible, e.g., because some of them run only in terminal emulator. A lot of them are listed at http://roguebasin.com.

Let me know if I can help in any other way.