Do you just encounter Dodoro once?
Viewing post in Secret Quest / Dodoro Guide
not sure if this thread is dead or not, but no you don't encounter even the cursed dodoro only once—it's just that you can just only visit the '???' location at night. i would get any necessary grinding done during the day, or just take naps until nighttime, and then head out to the cursed dodoro location. stock up on three or four 'orc's favorite dishes'.