I'm still surprised that A Penny For My Thoughts didn't inspire a big wave of imitators and hacks of the game for different genres. It does some really interesting, effective stuff with how to structure the storytelling and how to evoke a specific atmosphere through mechanics. If nothing else, the "ask two people what happens, then choose one answer to be true" thing could easily be used in many other games.
I'd love to see Ganakagok applied to other genres. I think it's core mechanics and concepts would be great when applied to things from space opera to alien abductions. The use of Tarot-like cards in that game is really smart, and could be used in almost any genre (basically, the dice mechanics use aspects of your character and the setting to decide who gets to interpret the Tarot-like card).
I like how Swords Without Master structures the game as conversation into specific phases and decides who says what when and how the tone dice work. But I hate swords and sorcery as a genre. So I would love to see it applied to other genres. Maybe even tell different sorts of stories. (I think you could use this over-the-top action adventure game to tell some interesting personal drama stories, but it would take some hacking to get there.)