That was really cool to play from start to finish! Designs and controls were really smart, and the lines and humor were great. I love that each boss had his own personnality, fitting their style, it really felt alive (especially that last boss slaming his desk and pointing orders, really nicely designed).
Most makeshift bullets were a good surprise, altho I didn't really get which item did what when combined, maybe partly because of the size of the items dropped (or mabe the shy yellow color) which made them harldy readable, especially when too far.
It also felt a bit hard to read the perspective to avoid bullets, but you kinda get used to it after some time, except for the last part of the final boss, which is a bit too crazy (I know something about having a crazy last boss ;) but it feels good and necessary), and after a few retries I ended up running in circles and (s)praying.
Amazing work, and really nice entry!