There are multiple ways to fight her, depending on the quality and quantity of your gear, and here are some of them:
Spread out your units in a way that some of your units draw out Fai's (heavily-armored boss of the level) fire, while the others attack her from the flank. Her armor is strongest at the front and weakest at the back.
Explosives work well in damaging armor. If you don't have enough grenades, lure her into the explosive barrels in the level and shoot it when she's close to it.
There are landmines in the level that you can pick up (by dragging and dropping to your inventory slot). Then you can right-click on the item to plant the landmine on the current position. Lure Fai near the mine, and it'll go boom!