Well, since you said you're still accepting ideas mid development, I figured why not add a wee bit more.
So I had an idea that interested me about the spider girl. Besides battling her as an enemy, would it be possible to have her as a seamstress that can tailor different outfits for Nene? I don't know what quests or materials this spidergirl would want from Nene but I think the idea could work. Or, her silk could also be used for crafting.
Regarding the removal of Bellatrix, perhaps you could use a tiger girl? Since cats have barbed penises, their mating is quite rough. And tigers in part are quite territorial. Which means this girl could be very aggressive and overpower Nene into submission and lock herself inside Nene while biting her neck. That could be one way for them to interact. And while we're at it, why not make her pupils into slit eyes and her mouth have fangs like these predators in real life. Just my ideas running...
Another idea could be a sticky plump dryad woman that can grow plant tentacles that squirts sweet sap/mucus. Her own penis could also produce a thick orange/amber sap that's also her semen, which is also the same liquid that she'll secrete from her breasts. This plant woman would sadistically paint Nene in her fluids since there's a lot of potential to trap Nene, we could also see multiple penetration or domination scenes. And to further make her different from teala, her skin tone could be any Non human color. Maybe green from too much chlorophyll...then again I'm not some crazy scientist. And she would have legs to walk around instead of being stuck in a flower
Now I know i mentioned an idea for a family cow farm that has different kinds of milking and mushroom harvesting, but what if we added breeding events as well? I wasnt sure if you were already going to implement this so I figured I'd mention it.
Let me know your thoughts Mofu.