Really want to try this but sadly my BitDefender is blocking the exe as it detects (correctly or incorrectly) malware in the exe. Sigh. Will try again with a later version. Game looks like it will be my cup of tea, so good luck with it! I will continue to follow developments - saw it on RockPaperShotgun btw
I'm sorry, I can only give you my word that so far nobody experienced any sort of malware-like issues and the game doesn't try to steal your data or anything - it's working completely offline.
However, I did find posts reaching as far back as 2013 which are also related to BitDefender - it even considered the Ren'Py itself (not the games, just the engine!) a false-positive. So I think it may be an issue that will never be fixed. : (