There is no "weird anti-trans stuff" in the game. Possibly a few stereotypes here and there for many different characters as the game has quite a high volume of parody/satire. Speaking for myself, I couldn't care less about how others lead their lives as I simply I wish for everyone to be happy no matter who they are, where they're from, what they do. (as long as they love me.)
Ah that's what I was wondering, given the game has a lot of characters parodying various tropes and stereotypes like you said, I did wonder if it was that or not. Thanks for the reply! Game is quite unapologetically dark in a very satirical way. Interesting breath of fresh air from the 'unintentionally dark' and the squeaky clean 'thou shalt do no evil' games.