We're still early in the development of the story and anything I say here could change, but as of right now...
While there are plans for the choices you make to have consequences later on, some more than others, the story itself is planned to be mostly linear and not an extremely branching story. The later we go into the story, the more different consequences of previous choices we will see! I have a few planned and I'm sure many others will still come up. Mind that this can vary a lot and can be a few lines of dialogue added or changed in accordance to a previous event all the way to an entire scene that only happens under certain conditions.
I guess I do recommend keeping a save where you make all the choices you want to make as Lust regarding Resnick and those around him. :)