Hey thanks! As far as ideas go, if you've played any of the "open world" styles of cyoas where you can freely move between locations, I think that would be interesting to try. I don't know if combat would really add much, but I've at least considered rpg mechanics like usable stats and inventory. There's also potentially switching to a dating sim or rpg maker format, which might complicate things a bit.
Ultimately I'd want to tell a story and build an interesting setting, while allowing the player to enjoy the sexy side of things. There is a story to the lab that could be further explored, but scaling the core idea of tailoring the experience to your preferences does turn into a lot of work when I'm writing 4-8 possible outcomes to each scenario. I also don't think it would continue to be a bad end simulator, I like the idea of continuing after being changed.