There should be a link to start the game. Is this on HTML or Windows? What resolution are you playing on?
Correct me if I'm wrong, it sounds like you are starting up the game, heading straight into the settings, and then when you try to Resume it gets stuck?
This is something I am in the process if fixing, but for now if you continue past the title screen to Start Game, you can load your game save (or create a new one) and should not encounter the error anymore.