Thank you for the report, and I apologize for not being able to respond earlier.
What is your OS(Windows, Linux or Mac)? Do you receive an alert from the game when you save? Are you able to load the game file immediately after you save? Do you run the game as administrator?
Try extracting the game folder into the program files folder in your C: drive and execute the game there. Also, when you save the game, test if you have the same issue if you soft restart the game with the F5 key.