Let me make an isometric test scene and get back to you on it since I haven't made a setup for isometric yet. At the very least, the rule check shape will need to be rotated the isometric angle but let me see if it's as simple as that or if some functions will need to be modded for isometric.
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I'm currently writing tests for an isometric demo. I had to add support for skew which is still only in my dev version (since isometric use irregularly shaped rectangles). Currently getting collisions to work nicely. If all goes well it will be the next update and there will be a guide on how to use it with isometric.