I really like the large assortment of kinky 3D environments! The idea of running though a sex business tower fetching items is certainly a fun one!
The play areas are a bit broad, which could work well with a map or direction markers, but if you want to keep the things simple, smaller levels may work better. Placing the player a bit closer to the top side of the screen will offer a bit better visibility since the perspective allows you to see more at the top and less at the bottom.
Enemies draining time away and leaving you with status effects is a really neat mechanic. I'm guessing that the main character's appearance will also change in future versions while you're under certain types of effects?
A good showcase of the gameplay, with really nice and varied 3D models for various departments!