I wanna quickly give some advice to anyone who uses Aseprite and a screen tablet like XP Pen (XP Pen 13.3 pro in my case), but before I do I just wanna say that this software is lovely and that it can help add so much more personality to someone's streams, it's helped with mine so far.
Now, if you're like me you might've noticed that for some odd reason the arm portion will sometimes stop tracking Aseprite movements when using the tablet but not for the mouse. If you're specifically in the Spud Arm screen itself it will track with the tablet, but swapping over to certain software while using the tablet will cause it to stop tracking. It took me a bit to figure out how to get around it, but for using Aseprite, I recommend turning off the "Windows Ink" mode for the Tablet. For some reason beyond my limited understanding (I'm a pixel artist, not a programmer, so this stuff's beyond me), Windows Ink, Aseprite, and the Spud Arm don't all like to play nice with each other all at the same time. The 'Ink' mode doesn't seem to interfere with any other art program's 'spud compatibility' to my knowledge (Procreate seemed to work just fine with it), but Aseprite seems to throw a fit with it. Thankfully though, pen pressure isn't really important for Aseprite (if it's even used at all), so you're fine to turn it off.
Basically for all my fellow Aseprite users with Tablet Screens:
Try turning off Windows Ink mode.
It might help ya out.