Who is the Red Queen, Lachesis or Atropos, and The Final Prize is Soup all have image descriptions/captioning.
I'm not sure what you mean by fully accessible. As mentioned, I don't disable the built-in Ren'Py accessibility features, which encompass:
- Keyboard navigation
- Self voicing
- Font override (at minimum: DejaVu Sans and Open dyslexic)
- Font size/spacing toggles
- High contrast text options
If unfamiliar with Ren'Py, you can access the accessibility menu via the 'A' keyboard key.