Sadly, itch does not do it. Not properly. I have seen files that were detected by virustotal, yet were hosted on itch.
My whole point is, that questions like this are prudent. There is several malware games a day that slip through the net and appear alongside the legit games. At the time the question was asked there might have been a surge of dlsite games. It almost was a sure bet, any game remotely looking like one was malware. I am not joking. If you go to recent adult games on a weekend you will find a dozen or more of that crap.