Honestly, IMO, the best thing to do for full NG+ support is to allow for players to win every fight that the plot mandates you lose, and unlock an alternate ending or something.
Depending on how strong Dealer is, maybe NG+ Vampire Mila could ACTUALLY beat what Dorian wants out of him? But hey, you don't have to. It can just be "start the game again with big stats and ignore the canon inconsistency"