Nice great game! It has a great eerie feeling to it and nice sound and music implementation. Graphics is simple but looks nice. I like that there is various biomes to explore.
I somehow lost one of the runes while trying to move them between containers.
Got an error when trying to go back to the first red planet to look for the third crystal.
[Error in put_entity (Red Planet - Lab Preload): Invalid entity.]
After killing the three cosmic horror entities their health bar was still there with a small amount of hp showing. After returning to the cryo chamber the game seems to restart in the same solar system, but as I understand you know this already.
Tiles are a bit small but it works. Movement could be a bit more snappy and/or queue up next input.
The game was a fun experience to play! Good job!