Quarantine/Isolation Simulator?
Whether the illness is, a game genre that the purpose of the player (and its characters) is to maintain isolated from something. This not only could be COVID-19, can be also Zombies or Aliens (for a classical), can be from music, books, videogames, TV, YouTube, Netflix, will be fun to isolated from your own sister/brother, husband/wife, friends, and so on. It's a theme that its topic can be extendable to anything, but still will be recognized by the users for the reasons why that theme.
Some Keywords could be:
1. Quarantine (daahhh!)
2. Isolation (as others purposed above)
3. Anything (Illness, addictions, creatures)