Sorry about my very late reply 😅, I haven’t been logged in into Itch.io for a while, so I didn’t see your message. If you still have the issue, and want to use Rem’s Studio, I recommend starting the engine from a terminal/console window: there, you can see the logs, and there will probably be some kind of error message.
You can post that here, and ideally your OS version and hardware, so I can get a clue about what’s causing the issue. (e.g. Intel iGPUs don’t support all OpenGL things, so I have to work around that; but personally, I don’t have an Intel iGPU for testing)