Yeah sorry about that, the Help & Tutorial is pretty bad atm.
You'll first need to check if the Meme file size is correct (compare between Upload-Info & Rulebook), if that is not the case you need to scan the Meme by selecting the Discrepancies; then you'll see if it contains a Virus (if yes, just select it in the Discrepancy Mode); however if you approve a Meme containig a Virus this leads to a random Minigame where you have to defend your system from the Virus.
Please note that this is an old Alpha Demo and is not up to date anymore (as stated below); if you want see how it currently looks you can check out my Kickstarter Page where i post weekly Updates :)