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There is little in the way of current ingame content on size difference. There are a few mentions I believe littered about (Particularly Rush and Artica). However, there is a popular mod called Hypertus which may appeal if size difference is the goal. I doubt there will be anything significant on size difference exactly but...

!!!!!SPOILERS FOR UPCOMING CONTENT!!!!

Additionally, while not directly size difference content, based on the Github actions page, the author is going to be adding a module on pills that have different transformative effects. Included in this line up is sizing up and down different body parts and changing some of the sliders of body type first in the game.

To have encounters with Alex, first complete the Portal Panties questline. After, go back to the engineer and ask him the non-purchase dialouge questions. At a certain point there is the option to ask to help him. He will intially decline but allow you to watch his work. Do this for a couple days until he opens up about furthering your relationship. Complete the submission questlines and on eventually he will gain enough trust to engage you in his last 'lessons'.
Another method is to duplicate a static NPC and enslave them using the Debug menu. It should do what it says on the tin and I think it doesn't have a limit on how many times you can do that, just be careful not to crash anything by messing with the variables.
There is also an Alex mod which extends his storyline a bit although it may not be up to date with the current version.

In settings there is an option to turn off the sensitivity feature included in the 0.1.7.1 patch. Main Menu >> Settings >> Difficulty settings >> Overstimulation mechanic

If playing with Debug/Cheats. Pull up the menu and there should be a button to remove all bondage (Except for the prison collar). There may also be an option to remove all pre-game opt-outs but not sure where that is. Otherwise, rydudex is correct.

For timeline progress, go to the linked Github page for BDCC. It has the project's active code. Alternations, additions, and updates are shown under the Actions tab. Look for new action logs from Alexofp (AKA Rahi). There you can see what the creator has been working on most recently! No official dates but something to tide us over until the grand reveal.