Hey there! Unfortunately I only accounted for 1920x1080 / 16:9 screens when making this game originally, and I currently do not have plans to update it in any way.
To get to the main game, you just need to press space to get past this screen and the comic panels right after. You will most likely have difficulties progressing as the objective info is on the top portion of the screen.
If I ever make a new game in the future, I will make sure to account for different screen resolutions. Sorry for the inconvenience.