FIST is the beautiful marriage of two philosophies of game design, which is then crashed by Hideo Kojima, and everyone who witnesses it will never forget it.
FIST has become the instant go-to for sessions when the whole group can't make it but we don't want to cancel. CLAYMORE is the master of the d66(6) table and uses it to great effect to make character creation happen in fifteen minutes and adventure generation happen even faster. I never feel put on the spot being asked to run FIST on even a moment's notice. In fact, I cannot wait to see what happens.
My players use a lot of different words after I run a session of FIST for them, but the sentiment behind them is always the same: that fucking ruled.