After opening the extracted folder, instead of opening the game, you have to right click on it and then click on "Show Package Contents". 

Inside will be a folder called "Contents", open it. 

Inside, open the folder titled "MacOS" and inside will be a program (pictured below) titled "Prank Masters". Running that program will open up a Terminal session which will open the game.

I hope that helps! :))

EDIT: I totally forgot about this method! Pandapandapop brought up a really good point, you can download the game on the itch.io app and launch it seamlessly using the itch.io desktop program. However, if you wanted to download the game file directly to your computer and not through itch.io, I'd suggest using the method above. ^^

I play on Mac and I have never had a problem opening the game or getting it to run. I just have the bugs that other people mentioned with the routes. 

All I did to get the game to run was download it through itch.io and click launch. Maybe it is different if you aren't using itch.io?