New & popular Simulationwith Mouse support (7,201 results)
Explore Simulation games with Mouse support on itch.io. Games that try to simulate real-world activities (like driving vehicles or living the life of someone else) with as much · Upload your games with Mouse support to itch.io to have them show up here.
New itch.io is now on YouTube!
Subscribe for game recommendations, clips, and more
Investigating a suspicious website, you and your partner uncover a horrifying truth
Simulation
Play in browser
Ever wonder how hard it is to win the lottery? Play through a lifetime of lottery draws
Simulation
Play in browser
Are you the best turtle breeder? Create the strongest child! Defeat your sister!
Simulation
Play in browser
A physics-based slope-jumping adventure set in a whimsical world. Can you can make it to the top of the leaderboards?
Simulation
Play in browser
Master the timeless art of bowling in this throwback to Wii Sports Bowling
Sports
Evolution simulation with dozens of configurable parameters in pygame
Simulation
"THOSE UNSATISFIED SPIRITS ARE WAITING FOR THEIR LAST DRINK, IT IS THY HOLY DUTY TO SERVE THOSE FOLKS"
Simulation
Can Neuro-sama free herself from her terminal-based digital prison?
Simulation
Your boss Big Fat Cat is blind and needs your help in sorting fish that he can eat. Will you help him?
Simulation
Play in browser
A Shop Sim / Creature Collector with geckos, and a small open-world city to explore.
Simulation
Stuff delivering on drone through government persecution in New York City in 2056
Simulation
Naev is a 2d action/rpg space game that combines elements from the action, rpg and simulation genres.
Role Playing
Carve your own path and make crucial decisions as you strive to leave a lasting mark on the world.
Strategy
You have been abandoned by the campus, there is only you here. No, there are many anomalies with you.
Role Playing
Loading more games...