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Latest featured Puzzleon sale with Mouse support (20 results)

Explore Puzzle games with Mouse support on itch.io. Games that challenge the player with critical thinking to solve levels. · Sell your games with Mouse support on itch.io to have them show up here.

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Puzzle deckbuilder
Puzzle
Play in browser
Add up, multiply, clone, and divide your party members to beat the monsters on your path!
Puzzle
a puzzle game set in liminal locations, with procedurally generated rooms.
Adventure
A sudoku-like with hexadecimal numbers and binary restrictions
Puzzle
Build bridges in the underworld.
Simulation
Boot up your Z5 Powerlance and dial into Last Call BBS, the last game from Zachtronics!
ZachtronicsVerified Account
Puzzle
An engineering game with cute robots!
Puzzle
A food-themed puzzle game where you have to arrange lunches in bento boxes!
Puzzle
Cellular Minesweeper Shooter 🔬
Puzzle
A puzzle game that makes a splash
Puzzle
A highly-stylised puzzle / tower defense hybrid with jazzy music
Puzzle
Use the MOLEK-SYNTEZ to create small molecules with various pharmacological effects.
ZachtronicsVerified Account
Puzzle
golf + cards + puzzles
Puzzle
It’s the assembly language programming game you never asked for!
ZachtronicsVerified Account
Puzzle
SHENZHEN I/O: BUILD CIRCUITS. WRITE CODE. RTFM.
ZachtronicsVerified Account
Puzzle
Master the intricate, physical machinery of the transmutation engine— the alchemical engineer’s most advanced tool!
ZachtronicsVerified Account
Puzzle
Build factories that assemble products for your alien overlords, and try not to die in the process.
ZachtronicsVerified Account
Puzzle
​The year is 1997. You used to be a hacker, but now you have the phage.
ZachtronicsVerified Account
Puzzle
An open-world puzzle game inspired by The Witness
Puzzle
SpaceChem is an obscenely addictive, design-based puzzle game about fake science!
ZachtronicsVerified Account
Puzzle
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