No. It needs to have a Game Boy style. Basically Pixel Art with a yellow colour. for 1996. Or Blue or Red for like a Pokemon red and blue from 1996 style.

it should run on actual game boy and or game boy color.

As RodrigoCard says, the entry MUST run on an actual game boy.

In more detail:

• The final deliverable must consist of a GB or GBC ROM file.
• GBC features are allowed (entries may be GBC only)
• SGB features are allowed (but don't rely on them)
• You can use RGBDS (ASM), GBDK (C), ZGB (C), GB Studio, GBSDK(C+RGBDS ASM) or anything that produces a valid ROM.