Hey there!
Not entirely sure about Cross Origin Isolation but make sure 'Ensure Cross Origin Isolation Headers' is checked when exporting Godot Web Build:
As for Shared Array Buffer, you should be able to either:
- Export the game as single-threaded by unticking 'Thread Support' in web export settings, this is a new feature in Godot 4.3-beta1 and may break the music/SFX in your game. This is what I used for my game and it has worked well.
- Or when uploading the game to itch.io for the first time you should be able to enable SharedArrayBuffer support. Here's some more info on how it works: https://itch.io/t/2025776/experimental-sharedarraybuffer-support